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✅ SUCCESS

1. At-Home Sedimentation Rate (SR) Measuring — Cor Health

What it does:

This tool allows at-home measurement of erythrocyte sedimentation rate (ESR), a well-established marker of systemic inflammation.

Why it matters long-term:

Inflammation is not something you “feel” until it’s too late. Being able to track trends over time—without waiting for lab appointments—adds real power to prevention. This helped me correlate lifestyle, travel, mold exposure, training load, and recovery with inflammation spikes.

I have been testing myself super regularly, but also my family and friends :)

Who it’s for:

People serious about longevity, chronic inflammation, autoimmune terrain, or environmental exposure tracking.

Who it’s not for:

Anyone looking for instant gratification instead of trend analysis.

Get yours with a super discount here : Val’s Faves with Discount Codes

2. Daily HBOT (Hyperbaric Oxygen Therapy) — Oxy Health Vitaeris

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What it does:

HBOT increases oxygen availability under pressure, enhancing tissue oxygenation, mitochondrial efficiency, angiogenesis, and cellular repair.

Why it earned its place:

Used consistently, HBOT improved recovery from intense training, long-haul flights, sleep deprivation, and heavy cognitive load. Oxygen is not a “hack”—it’s a fundamental biological lever, and HBOT amplifies it safely when used correctly.

Who it’s for:

Athletes, frequent travelers, people optimizing recovery, brain health, or inflammation.

Who it’s not for:

Those expecting overnight miracles without consistency.

Get yours with a super discount here : Val’s Faves with Discount Codes

3. CAROL Bike

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What it does:

Uses AI-driven resistance to deliver extremely short, maximal-effort sprints designed to stimulate VO₂ max and cardiovascular adaptation.

Why I kept it (despite skepticism):

As someone with decades of endurance training, accepting that 5 minutes could rival 45 was… uncomfortable. But VO₂ max is one of the strongest predictors of longevity, and this delivered a potent stimulus with minimal joint stress and time commitment.

Who it’s for:

Busy high performers, aging athletes, anyone focused on cardiovascular longevity.

Who it’s not for:

People who hate intensity or don’t respect recovery.

Get yours with a super discount here : Val’s Faves with Discount Codes

4. Oura Ring

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What it does:

Tracks sleep stages, readiness, body temperature trends, HRV, and recovery using overnight biometric data.

Why it changed my habits:

I didn’t need more data—I needed better sleep decisions. Oura helped me connect light exposure, dinner timing, stress, travel, and supplements with real sleep outcomes. That alone justified its place.

Who it’s for:

Anyone serious about sleep, recovery, and circadian health.

Who it’s not for:

People who obsess over scores without changing behavior.

Get yours with a super discount here : Val’s Faves with Discount Codes

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5. Hydrogen Therapy — Axiom H2 (Water + Inhalation)

What it does:

Delivers molecular hydrogen, a selective antioxidant that reduces harmful oxidative stress without blocking beneficial signaling pathways.

Why quality mattered:

Low-end hydrogen bottles don’t deliver therapeutic concentrations. Professional-grade systems changed everything. Hydrogen supported recovery, inflammation control, mitochondrial efficiency, and travel resilience—especially via inhalation.

Who it’s for:

Those dealing with oxidative stress, inflammation, heavy training, or frequent travel.

Who it’s not for:

Anyone tempted by cheap gadgets instead of verified output.

Get yours with a super discount here : Val’s Faves with Discount Codes

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6. NADH / NAD⁺ Support — BioBloom US (Patches & Injectables)

What it does:

Supports cellular energy, mitochondrial function, and DNA repair by replenishing NAD⁺ levels, which decline with age.

Why delivery method mattered:

After years with NR and NMN, transdermal patches—and injectables when appropriate—provided faster, more noticeable effects by bypassing digestion. Energy, resilience, and cognitive clarity improved measurably.

Who it’s for:

Advanced biohackers focused on aging biology and cellular energy.

Who it’s not for:

Beginners skipping foundations like sleep, nutrition, and stress control.

Get yours with a super discount here : Val’s Faves with Discount Codes

❌ FAILS

7. WHOOP

What it does:

Tracks strain, recovery, and sleep via a subscription-based wearable.

Why it failed in real life:

Unreliable without signal, non-transferable annual membership, and overly generous sleep scoring made it incompatible with serious measurement—especially during travel and field testing. Did not work while I was in the middle of Tanzania, without a signal for 3 weeks. Stop synchronizing all data after 3 days.
Also, as a woman who likes to change my style, having the same bracelet over and over does not fit my life: Red Carpet event? Cannot wear. Going out to a meeting wearing a sleeveless dress? Looks “weird” and “mismatched”, etc….

I tried to give it to my dad after a 3-mont test. I learned that my prepaid year membership was NOT transferable. This qualifies as a scam in my books.

Lesson:

If data can’t be trusted everywhere, it can’t be trusted anywhere.

8. CGM (Stelo / Dexcom)

What it does:

Estimates interstitial glucose levels continuously to infer blood sugar trends.

Why it failed for me:

Repeated discrepancies versus finger-prick testing created misleading narratives. Data noise without context is worse than no data at all.

Ex : reading on Stelo: 183, reading on the finger-prick device, 139.
Fasted glucose with a regular blood test: 76. Every morning for 15 days with the Stelo? 110 ! That’s pre-diabetic!

Lesson:

Measurement precision matters more than measurement frequency.

🧭 My 2026 Biohacking Roadmap

2026 is not about adding more tools—it’s about refining signal, reducing noise, and going deeper.

🔬 What I will continue

• Daily HBOT

• Hydrogen therapy (inhalation + water)

• NAD⁺ optimization with NADH (targeted, not constant)

• Sleep optimization with Oura

• Inflammation tracking via SR

🧪 What I will test next

• Libre 3 CGM (to reassess CGM accuracy)

• Deeper mitochondrial function markers

• Expanded brain resilience & neuroinflammation tools

• More precise VO₂ max and cardiovascular aging metrics

• Expand on my peptide usage

• Try more of the HOCATT

• Increase my usage of N1o1 nitric oxide and monitor specific markers

❌ What I will avoid

• Trend-driven wearables without validation

• Tools that increase anxiety instead of insight

• Subscription models that lock users without flexibility

🧠 Final Word

Biohacking is not about gadgets.

It’s about biology, consistency, and humility in front of data.

Some tools earn their place.

Others don’t.

👉 You’ll find my validated favorites and exclusive promo codes on ValerieOrsoni.com.

The long game always wins. 🧬

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Valérie Orsoni
Biohacker since 1998 | Longevity Expert

Instagram : @valerieorsoni

My fave brands + super promo codes here ==> ValerieOrsoni.com

🎙 Longevity Leadership Conference – Verizon Innovation Lab, Los Angeles - Mar 18–19, 2026)
🎤 Biohackers World Conference & Expo, Los Angeles (Mars 28-29, 2026)
🎙 HealthSpan Summit, Los Angeles (Oct 2–4, 2026)
🎙 Reclaiming Health & Longevity Symposium (El Salvador, Nov 8–9, 2026)

Disclaimer: This article reflects one individual’s personal experience, research, and interpretation of scientific information. It is not medical advice and should not be used as a substitute for professional diagnosis or treatment. Health conditions—whether metabolic, hormonal, digestive, neurological, cardiovascular, immune-related, or otherwise—can vary widely in severity and may require urgent or specialized medical care. Always seek advice from qualified healthcare professionals before beginning, changing, or discontinuing any medication, supplement, lifestyle protocol, or therapeutic approach. Personal experiences described here, including mild or atypical presentations, are not representative of all clinical situations or of serious or acute medical conditions requiring immediate attention.

Be warned: This is a very long article with a ton of information. Enjoy your reading!

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Picture this: You’re standing in your living room, using a device the size of a glucose meter. Ten minutes later, you have a precise measurement of systemic inflammation coursing through your body—the same test that, until recently, required a lab appointment, a phlebotomy needle, and 48 hours of waiting.

In July 2025, that test showed my inflammation at 24 mm/hr—not dangerous, but silently accelerating my biological aging. Four months later? 4 mm/hr. Ultra-optimal. My body is now aging at 72% of the normal rate.

Because unlike most inflammatory markers that give you a vague sense of “inflammation,” ESR provides precise, actionable, trackable data that correlates directly with longevity.

Let me show you why this matters, what affects it, and exactly how I hacked mine.

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As I mentioned in the intro, they’re said to repair skin, stimulate collagen production, erase wrinkles, and even “rejuvenate cellular youth.”

In the biohacking world, exosome injections are a thing — yes, really.
So why not cross over from injections to beauty creams? Many actives can work both through injection and transdermal application… so why not exosomes?
I dug into the subject for you.

So… do they work or not?

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For the first time ever, scientists have shown that we can actually increase the brain’s production of acetylcholine — the neurotransmitter of attention, learning, and plasticity — through targeted brain training.

And the result? Participants’ brains produced as much acetylcholine as those of people 10 years younger. That speaks directly to my biohacker’s mind (well, brain).

Because yes — for a biohacker, this is groundbreaking.
Let’s dive in and find out how we can replicate this study in the comfort of our home!

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But what if I told you that you can improve it by 12% in just a few weeks, without spending hours sweating on a bike (like, 3 x 5 min per week!).

That’s exactly what I’m going to test.

🚲 My Starting Point

I just received my CAROL Bike, a workout bike unlike any other.
It’s the first one to offer REHIT (Reduced Exertion HIIT) at home — a method that, until now, was only available in laboratories.

At the moment, my VO₂max is 41, which is already excellent for my age (55).
But my goal is clear: reach 46–47 ml/kg/min, about a 12% increase — exactly what the CAROL Bike’s REHIT protocol promises.

💡 Why VO₂max Matters

VO₂max (maximal oxygen consumption) measures how much oxygen your body can use during intense effort.

The higher your VO₂max, the more efficient your cardiovascular and respiratory systems are.

It naturally declines by about 10% per decade after age 30.

Research shows that a 10% increase in VO₂max can reduce mortality and morbidity risk by 15%.

And according to scientific data cited by CAROL Bike, the REHIT protocol can increase VO₂max by 12% in 8 weeks— the equivalent of reversing 10 years of cardiovascular aging!

🧮 What’s a “Good” VO₂max by Age and Gender?

The following values come from the Cooper Clinic (Dallas) and the American College of Sports Medicine (ACSM) — the most widely used references in research and fitness testing.

💡 Quick guide:
🟢 Average — general population, no specific training.
🔵 Good to excellent — active lifestyle, healthy heart.
🟣 Athletic — endurance athlete, disciplined biohacker… or, well, your favorite coach 😄

➡️ For a 55-year-old woman, a VO₂max of 27–30 is average, 34–38 is excellent, and >39 is outstanding.
So with 41 ml/kg/min, I’m already in the athletic category for my age group — proof that consistency and effort pay off 🎯

🔬 What Is REHIT?

REHIT (Reduced Exertion High-Intensity Training) is an optimized form of HIIT:

• Two 20-second all-out sprints

• Separated by recovery phases

• The whole session lasts under 5 minutes, done 2–3 times per week

👉 This protocol triggers a powerful metabolic response — activating mitochondria, boosting EPOC (post-exercise oxygen consumption), and improving cardiovascular capacity faster than traditional cardio.

The secret behind the CAROL Bike is its AI system and instant resistance adjustment.
It adapts the load within milliseconds to push you to your maximum effort threshold — safely, without overtraining.

Traditional bikes just can’t respond that fast — which is why true REHIT is hard to replicate elsewhere.

For everyone who tells me they can “do REHIT” on their Peloton or another bike — you can mimic it, yes, but not achieve the same precision or results.

📈 My 8-Week Protocol

I’ll be sharing my progress each week:
my metrics, my sensations, and the adjustments I make to stay in the optimal progress zone without overdoing it.

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🧠 What the Science Says

A study on the CAROL Bike shows an average 12% increase in VO₂max in just 8 weeks.

Post-exercise metabolism (EPOC) remains elevated much longer than after a regular cardio session.

Independent user reports also confirm similar gains (+12% in about 10 weeks).

And most impressively — it takes 90% less time than traditional cardio!

I’ll admit — I was skeptical at first.
But after reviewing several credible studies and feedback from sports medicine doctors, I thought: only fools never change their minds.

So I reached out to CAROL to test their bike transparently and document my results.

This two-month experiment was inspired by their “Most Innovative Exercise Bike 2022” award — and I’m ready to see if it lives up to the hype.

⚙️ Why Other Bikes Can’t (Yet) Do This

• Instant resistance: most bikes can’t adjust load within milliseconds.

• Adaptive AI: CAROL continuously analyzes your power and adjusts each sprint.

• Integrated safety: the system manages intensity peaks without pushing beyond your limits.

🌿 In Conclusion

I’m starting this 8-week experiment to boost my VO₂max by 12%, with a clear goal — going from 41 to 46–47.

If the promise holds true, it will prove that we really can rejuvenate our cardiovascular system… in just 5 minutes, 3 times per week.

I’ll be sharing my results weekly — VO₂max curve, recovery, sleep, heart rate, and of course, my full biohacker experience 💪

💬 And if you want me to show you how to measure your VO₂max at home, let me know in the comments 👇

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Valérie Orsoni
Biohacker since 1998 • Longevity Expert
👉 @valerieorsoni on Instagram
👉 LiliWarrior.com — 100% recycled, non-toxic activewear (hurry, and grab what you like, we will soon close our US-based operations, keeping Europe and Asia, because of the tariffs that do not allow us to be profitable anymore).

🎙 Speaking engagements:

• Biohackers World Conference, Miami — Nov 1–2, 2025

• Reclaiming Health & Longevity Symposium, El Salvador — Nov 11–12, 2025

• Longevity Leadership Conference, Los Angeles — Mar 18–19, 2026

• Sommet de l’Hypersanté, Paris — Mar 21–22, 2026

• HealthSpan Summit, Los Angeles — Oct 2–4, 2026

🧬 When it comes to longevity and youthfulness, biohackers tend to focus on cold plunges, peptides, mitochondrial optimization, and NAD+ boosters.

But one surprising (and often overlooked) accelerator of aging?

Cheating on your partner.

In this article, we explore how betrayal behavior contributes to premature aging at the hormonal, neurological, mitochondrial, and even genetic levels.

As always, we ground this in science, not speculation.

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You might be thinking: “I’m not a biohacker.”
And yet… if you’ve ever taken a step back during a stressful situation, if you’ve chosen health, adaptation, resilience — then just like Molière’s Monsieur Jourdain spoke prose without knowing it, you’re already doing biohacking without even realizing it 😉

🔥 The core principle? Reducing inflammation. Always.

The ultimate goal of a biohacker is to reduce systemic inflammation as much as possible — because it’s the root of nearly every chronic illness, from accelerated aging to immune dysfunction.

And guess what?
➡️ Acute stress, especially emotional, is the #1 source of inflammation.
So: staying calm, no matter what happens, is a powerful cellular hack.

🚨 The Incident

While I was giving a talk at the SUPYoga Festival in Marseille — on the topic “Running as Therapy? Endorphins, Dopamine & Biohacking” — just a few hundred meters away, my father’s car was broken into.
He had come to join me for the event.

In broad daylight. In a busy, touristy area.
The car was locked, nothing visible… and yet: the back window was smashed, the trunk forced open, and his suitcase was stolen.

💼 What was in that suitcase?

• All his clothes for our upcoming biohacking retreat in Tunisia

• His biohacking devices (Apollo Neuro, HeartMath, Oura Ring, etc.)

• And most of all… the STEMREGEN I had been waiting impatiently to test and document!
  On top of that, our original plan was to leave the car at the airport with my non-essential bags safely hidden in the trunk…

🤯 A few possible reactions…

🧟‍♀️ Drama Queen Mode:

"This is a disaster. The trip is ruined. I’m losing it!"

😩 Victim Mode:

"Why us? It’s always us. Only our car was hit!"

🧠 Biohacker Mode:

"Okay, this isn’t fun. But what’s the upside? What can I let go of? How do I avoid that cortisol spike I really don’t need?"

✨ What I chose to see:

• My dad wasn’t hurt — the most important thing

• His credit card, which he had left in the car, was not taken

• His breathing device, inside a small bag in the trunk, was also untouched

• Our flight, originally scheduled for 9 a.m., was delayed to 5 p.m. → leaving us time to buy what we needed

• A dear friend, Caroline (co-organizer of the festival and of CoWellness), kindly offered to store my car and excess bags for the week — women supporting women in action 💪

🎯 Being a biohacker doesn’t mean being happy bad things happen.

It means choosing to put things in perspective.
It means refusing to feed stress that serves no purpose other than to inflame your body and cloud your mind.

It also means reconnecting to what really matters:

If my only “drama” is a stolen suitcase while others are facing war, persecution, or survival... do I really have the right to spiral?
My answer is no.

Plus — we have the means to buy another swimsuit, a pair of linen shorts, some fins, and continue our journey.
Human connection > stolen things.

💞 My Evening Meditation: The 5 Circles of Love

To close this chaotic day, I meditated with a ritual I often use:

1. ❤️ I send love to my inner circle — my son, my partner, my parents

2. 💕 To my closest friends

3. 🤝 To people I regularly interact with (neighbors, shop owners, online friends…)

4. 💫 To those I barely know but who need support

5. 💔 And finally, to those who have hurt me — the most difficult, but also the most healing

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🧬 In moments of acute stress, my go-to biohacks:

To help the body return to balance:

• ✅ Liposomal Vitamin C (LiveOn): powerful antioxidant and cortisol buffer
  → "Effects of ascorbic acid on cortisol response to physical stress," Brody et al., Psychopharmacology, 2002 – PMID: 12373496

  

• ✅ Hydrogen-rich water with my MitoRedLight bottle → reduces oxidative stress
  → Ohsawa et al., Nat Med, 2007 – PMID: 17486089

  

• ✅ HeartMath coherence breathing (use code ORSONI for 25% off)

• ✅ Alternate nostril breathing (nadi shodhana)

• ✅ Warm foot bath + Epsom salt

• ✅ Nature walks + 10 minutes of sunlight without sunscreen

• ✅ And of course… writing, gratitude, and sharing

🌍 And now?

I’m publishing this article.
Letting the thoughts settle.
And heading off with my dad for a week of biohacking in Tunisia, light-hearted and full of perspective.

(I am wearing my Apollo Neuro, my Oura Ring, my LiliWarrior 100% recycled sunglasses, and you can see my MitoRedLight hydrogenated water bottle).

A few thieves won’t ruin our father-daughter time.

Oh, and I almost forgot…
The day before the break-in, I received absolutely incredible news…

🎤 I’ve officially been invited to speak at RAADfest!

The RAADfest is the longevity and biohacking event of the year.
👉 No speaker can pay to be on stage.
👉 You must be invited, recognized for your expertise and contribution.
It’s basically the Holy Grail of biohackers — and I’ll be there 🙌✨
(And yes, the invitation message was amazing…)

Forza! 💪
Now tell me — what was your last biohacker response to a stressful moment?

Valérie Orsoni
Founder – ValBiohacker.com | Longevity Explorer | Biohacker since 1998
Follow me on Instagram @valerieorsoni

I’d even go so far as to say: PWS should be included in every biological age assessment formula.

Ever since I discovered its significance, I’ve been tracking this number weekly. The best part? You can actually improve it with a few accessible, lifestyle-based interventions.

Honestly, I don’t understand why more doctors aren’t talking about this.

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You’ve seen it all over TikTok—countless influencers claiming brain flossing changed their lives. Tens of thousands of videos on the subject… I had to dive in and find out what it’s all about.

Inspired by the idea of flossing for oral hygiene, brain flossing suggests that you can "cleanse" your brain regularly to enhance mental clarity, focus, and even prevent neurodegenerative diseases.

Hoax? Miracle? Reality? Let’s find out.

Beyond the studies brain flossing advocates quote — is this just a trend, or is there real science behind it?

Could brain flossing actually be revolutionary and save our brains?

Let’s explore this new biohack.

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ZERO. NADA. NOTHING. NEVER.

I have never had a single drop of alcohol in my life.

When I was a teenager and 100% of my friends were drinking beer, cocktails, or wine, I was the “grandma” of the group. On top of that, I didn’t smoke either.

I must have had some sixth sense about how sugar-laden alcohol is… because I just never drank.

But how many times did I hear, “Red wine in moderation is healthier than water,” or “You just don’t know how to have fun!” As if “fun” required drowning yourself in alcohol.

Breaking the Myth: The 2021 Study That Changed Everything

In 2021, a groundbreaking study shattered this long-held belief. Let me walk you through it.

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If you've been following me on Instagram @valerieorsoni, you've seen me spend hours in a hyperbaric chamber, especially when I was healing my broken right ankle at super-speed 🦵💨.

I’m a big fan! 🌟 After talking to people around me, I realized very few understand how it works and, more importantly, why it plays a key role in biohacking and holistic anti-aging approaches. 💡

This post focuses on the anti-aging benefits, with future posts dedicated to autism, injuries (and how I healed my broken ankle in 5 days!), and more.

Let’s us dive into the fascinating world of hyperbaric chambers! 🫧

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For years, biohacking pros have been warning against seed oils. At first, I was skeptical and dismissed their claims. But then, I put on my nutrition detective hat 🕵️‍♀️ and investigated the truth. Is it fact or fiction? Here's what I found out…

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For months, I’ve been biting my tongue 😬, trying to stay polite, as I scroll through the nonsense 🤯 being shared in some sensationalist media 📰, and let’s be honest, all over the web 🌐.

The ridiculous claims made by so-called doctors or nutrition experts that you might stumble upon really remind me of the early days of microwaves—people used to belie…

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Did you know? Lack of sleep or regular disruptions (night shifts, nurses, police officers, firefighters, on-call doctors, etc.) can have dramatic health consequences.

Even missing just one hour can throw your health off balance and impact your life expectancy—far more than you might think!

At the end of this article, I’ll share my 7 steps to improve your sleep in just one week.

Alarming Statistics

• Losing one hour of sleep 🕑: Losing an hour of sleep can reduce your ability to process information by 32% 📉 and increase the long-term risk of heart disease 💔 by 23%.

• A sleepless night 🌙: One sleepless night reduces the efficiency of immune cells 🦠 (NK cells) by 70% and raises cortisol (the stress hormone) levels by 30% 😓.

• Regularly interrupted sleep 🚨: Frequent wake-ups increase the risk of diabetes by 16% and mood disorders 😔 by 60%.

• Impact on immunity 💤: Sleeping less than 6 hours a night triples the risk of catching a cold 🤧, as lack of sleep lowers cytokine production, proteins that fight infections.

• Impact on obesity 🌑: People who sleep less than 5 hours a night 🌑 are 50% more likely to become obese 🍔 than those who sleep 7-8 hours.

But What Exactly Is Sleep, and What Is Its Purpose?

Sleep is a natural state of rest essential for physical and mental recovery.

It is structured into several cycles, each with different stages:

• Light sleep (stages 1 and 2): The body gradually relaxes, and heart rate slows.

• Deep sleep (stage 3): This is when the body regenerates most, repairing tissues and boosting the immune system.

• REM sleep: Characterized by rapid eye movements, this is the phase where dreams occur, and memory is consolidated.

Each phase plays a critical role in overall health, cognitive performance, and longevity. A lack or imbalance of these stages can have harmful long-term effects on health. This is why consistently short or interrupted nights age us faster than nature intended.

Night shifts, disrupted, or short sleep can have significant health impacts.

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Hold on! Not so fast! 🛑 What if the way you walk affects the health of your skeleton? 🤯

Think about it: if your gait is incorrect, millions of misaligned impacts can eventually damage your joints, especially in the knees and hips. 🦵🦶

Do you think you need to wait until you're 75 to worry about this? Wrong! ⛔ It's the repetition that creates long-term problems. The sooner you correct your gait, the less likely you are to suffer later. 🕒

So, how do you know if you're walking CORRECTLY? 🧐

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Its ability to reduce hot flashes is well-documented.

In countries like Germany, this supplement is a cornerstone treatment for hot flashes.

Yet, in France, it remains relatively unknown despite its effectiveness and lack of side effects.

In the USA, it’s primarily used by those seeking natural remedies, but it’s rarely prescribed by doctors.

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