Inside My April 2026 Supplement Stack (The Logic Behind Every Choice)

I take supplements. A lot of them. Because I know how much a normal life, intelligently supplemented, can become an optimal life.

Reassessing your supplement protocol is a biological necessity — not a whim

I reassess my supplement protocol every single month.

I spend about 4 hours over a weekend doing so. This does not include the time spent reading and analyzing studies throughout the month.

This approach may surprise some people, but it is based on a very simple biological reality:

👉 The human body is not a static system.

Needs evolve depending on:

• environmental stressors (toxins, infections, travel, mycotoxins)

• inflammatory status

• gut permeability

• mitochondrial function

• autonomic nervous system balance

• and the adaptations induced by the supplements themselves

  

  

A protocol that made perfect sense three months ago can become useless, excessive — or even counterproductive — today.

To those who believe that “eating well is enough,” my answer is twofold:

First, our soils are severely depleted, meaning the foods we eat today are far less nutrient-dense than they once were.

Second, while a perfectly balanced diet allows you to live a normal life, a balanced diet plus intelligent supplementation allows you to live an optimal life.

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The physiological reasons behind changes in my protocol

Monthly adjustments are mainly driven by three situations:

1. A therapeutic objective has been reached

Example: targeted work on mycotoxins, which becomes unnecessary once biomarkers return to normal. I still have the OTAs to take care of though.

2. Controlled exploration of new molecules

Some emerging supplements show interesting mechanisms of action (mitochondrial, inflammatory, neuro-immune). I choose to test them in a measured, monitored, and controlled framework.

3. Conditions poorly or insufficiently addressed by conventional medicine

Or situations where I aim to avoid treatments with heavy side effects, when structured alternatives exist.

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This protocol is personal, experimental, and monitored

The protocol presented here is strictly my own.

It is:

• not a recommendation

• not a model to replicate

• not medical advice

It is an individual case, based on:

• specific medical history

• specific symptoms

• biomarkers that are regularly tracked

I share it solely because so many of you ask me what I take, why I take it, and how.

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Prescription molecules: framework and precautions

This protocol intentionally includes prescription-only molecules, known for their powerful systemic effects.

Example: colchicine

It is used here to modulate chronic inflammation, notably via inhibition of the NLRP3 inflammasome pathway, which is now well documented in inflammatory, metabolic, and neurodegenerative conditions.

👉 But colchicine is not benign:

• it can impact pancreatic function

• it requires regular lipase monitoring

In my case:

• a moderate elevation in lipase led to an initial 75% dose reduction

• that reduction was accompanied by a rebound in inflammatory markers

• a subsequent adjustment to 50% of the dose was then implemented

This is exactly how any serious approach should work:

observe → measure → adjust → reassess

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Formulation logic: absorption and digestive load

One often overlooked aspect: the form of supplements.

Whenever possible, I favor:

• powders

• liquid forms

• transdermal forms

Objectives:

• reduce digestive burden

• improve bioavailability

• avoid excessive capsule ingestion (currently ~80–100/day)

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“What about your liver? Your kidneys?” — a biological answer, not an emotional one

This question comes up often — sometimes sarcastically — often from people sipping cocktails or enjoying processed foods.

My answer is simple:

👉 I measure.

• Liver function

• Kidney function

• Inflammatory markers

Everything is tracked and documented.

And most importantly:

I publish the results — unfiltered, no storytelling, no spin.

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Supplement quality: a central issue

The scientific literature is clear:

👉 Supplement quality varies enormously.

That is why:

• I detail my choices on valbiohacker

• I am using as much as I can my own products though my line is very short on ZellNova.com (made in the USA, no fillers, clean).

  

  

Few products, but:

• verified manufacturing chains

• maximum traceability

• coherence with a serious biohacking approach

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April protocol: intentionally restricted access

The detailed protocol (timing, dosages, combinations, prescription molecules) is placed behind a paywall.

Not out of elitism.

But to avoid:

• superficial reading

• misuse

• and, above all, dangerous misinterpretations

👉 Only those truly committed to understanding can access it.

In this protocol, you will not see the BioBloom NADH patches I use twice per week.
Nor will you see the SomaPeptides peptides I use under fairly complex protocols.
Follow the links to access the exclusive discounts I negotiated for you.

Those require a dedicated article.

If peptides interest you, head to the PEPTIDES section on valbiohacker.com

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Why this protocol is heavily modified this month

The past six months were focused on mycotoxins (I eliminated all of them except one originating from tea, spices, alcohol, and coffee).

As a result, for April I reduced all binders (chelators) to zero except for charcoal which I am keeping in the morning.

I also aimed to eradicate salmonella without antibiotics, which I successfully achieved based on my latest test results.

Therefore, several supplements are no longer necessary (like oregano oil).

I have also removed all biofilm disruptors for now as I am embarking on a long 3-month trip and I cannot take every single supplement.

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Here is my updated list: