The Ultimate Guide to Biohacking & Longevity

The Ultimate Guide to Biohacking & Longevity

When Your Epigenetic Age Says One Thing, But Your Lungs Say Another: My Wake-Up Call

How comprehensive clinical testing revealed the truth behind alarming proxy measurements—and why biohackers need both data streams

Valerie Orsoni Biohacker's avatar
Valerie Orsoni Biohacker
Jan 07, 2026
∙ Paid

Warning: This is a LONG article with a ton of info and actionable items. I am sharing my personal lab results as well as I am super open to where I stand when it comes to longevity & biohacking.

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THE ALARMING DISCOVERY

In July 2025, my TruDiagnostic Advanced Age report delivered a gut punch: my FEV1 (Forced Expiratory Volume) percentile ranked at 11.9%—meaning my lung function appeared worse than 88% of women my age. As someone who skis to the South Pole, climbs 14,000-foot peaks, and dives 120+ feet underwater 100+ times annually, this made zero physiological sense.

But here’s where precision medicine gets interesting: that measurement wasn’t from actual spirometry. It was an epigenetic proxy—a DNA methylation pattern predicting lung function based on population data. And proxies, I was about to learn, don’t always tell the complete story.

But then, I traveled to Berlin, Germany to spend a full day of testing my body inside out…

Berlin, Germany, [YEARS]: The Ultimate Longevity Testing Experience

Valerie Orsoni Biohacker
·
September 16, 2025
Berlin, Germany, [YEARS]: The Ultimate Longevity Testing Experience

Walking into the YEARS longevity clinic in Berlin felt like stepping into the future—not some sterile, intimidating medical facility, but a warm, luxurious haven designed for deep, personalized health exploration. 📖✨ The Ultimate Guide to Biohacking & Longevity is a reader-supported publication. 💌 To receive new posts and ❤️ support my work, consider…

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AND……THE DISCREPANCY THAT CHANGED EVERYTHING AND GAVE ME HOPE

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