Archive - The Ultimate Guide to Biohacking & Longevity

From 15 Lesions to 9: How I Reversed “Irreversible” Brain Damage

This was serious stuff... the toll of the mountains, of life itself, of blows to the head, of age, and so on... They told me "it's not reversible"... I…

19 hrs ago • Valerie Orsoni Biohacker

September 2026

[LIVE] Osteoarthritis, how to reverse the irreversible

Our weekly live.

Sep 30 • Valerie Orsoni Biohacker

33:43

“Your skin looks amazing… what did you do?” My 8 skin changes, and my new obsession: the lower face

If the eyes are the window to the soul, then the skin is the window to your lifestyle, and a few other things… which I’m revealing here.

Sep 27 • Valerie Orsoni Biohacker

[Live] Fall, Energy, Menopause, my hacks to identify and fix your symptoms (and the mistakes to avoid)

Welcome to my FIRST ever live on Substack! Thank you for your support.

Sep 23 • Valerie Orsoni Biohacker

40:58

META Banned Me. My Answer? I’m Going LIVE Here Every Wednesday.

Cannot wait to go live with you!

Sep 21 • Valerie Orsoni Biohacker

You Track Your HRV Every Morning. This Takes Decades to Show Up

What 85 years of Harvard data say about happiness, health, and the relationships that shape how we age.

Sep 20 • Valerie Orsoni Biohacker

The Longevity Genetic Exception Hiding in Amish Blood

One extended family, one broken gene, and a story that took 25 years to become a longevity study and yes it is me on the cover photo :)

Sep 15 • Valerie Orsoni Biohacker

Sunday Note 🌿 Getting Back Into Exercise After a Long Break: The 3 Mistakes That Put You Right Back on the Bench

Want to move again? Ready to shake off the sedentary stre

Sep 13 • Valerie Orsoni Biohacker

I Have a Connected Cooling Mattress Topper. It Changed My Life!

When it’s hot out, sleeping (and especially falling asleep) becomes a real “project”! I found a solution that changed my life!

Sep 10 • Valerie Orsoni Biohacker

How I Improved the Way My Lungs Work by 74% in Nine Months

A look inside my Berlin pulmonary function tests, 9 months apart and how the numbers have dramatically improved.

Sep 7 • Valerie Orsoni Biohacker

The Top 14 Prescription Drugs With Dangerous Side Effects (2026 Blacklist)

What a leading independent drug safety report reveals. Numbers when they exist, honesty when they don't.

Sep 2 • Valerie Orsoni Biohacker

August 2026

Will IU1 Let You Live to 250?

I have seen everywhere: The magic pill that will help us live until 250. So...I started digging, and digging....and fell in the rabbit hole. This…

Aug 28 • Valerie Orsoni Biohacker

#nojs-banner { position: fixed; bottom: 0; left: 0; padding: 16px 16px 16px 32px; width: 100%; box-sizing: border-box; background: red; color: white; font-family: -apple-system, "Segoe UI", Roboto, Helvetica, Arial, sans-serif, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol"; font-size: 13px; line-height: 13px; } #nojs-banner a { color: inherit; text-decoration: underline; } This site requires JavaScript to run correctly. Please turn on JavaScript or unblock scripts